Prodoct Information
Product Information
|
Protein full name |
Mitogen-activated protein kinase 1 |
|
Synonyms |
APK1, ERK, ERK-1, ERK-2, ERK1, ERK2, ERT1, MAPK1,MAPK3, P42MAPK, P44MAPK, PRKM1, PRKM2, p44, p42, p44-MAPK, p42-MAPK, P-ERK, P-ERK1/2, P-ERK1, P-ERK2 |
|
Immunogen |
KLH conjugated Synthetic phosphopeptide corresponding to Human ERK1 (T202/Y204) + ERK2 (T185/Y187) |
|
Uniprot ID |
P63085 |
|
Isotype |
IgG |
|
Purity |
Affinity purification |
|
Predicted MW. / Observed MW. |
41/43 kDa / 42/44 kDa |
Applications
|
Applications |
Species |
Dilution |
Positive Sample |
|
WB |
Human, Mouse, Rat |
1: 400-1: 800 |
lung, kidney |
Background
Serine/threonine kinase which acts as an essential component of the MAP kinase signal transduction pathway. MAPK1/ERK2 and MAPK3/ERK1 are the 2 MAPKs which play an important role in the MAPK/ERK cascade. They participate also in a signaling cascade initiated by activated KIT and KITLG/SCF. Depending on the cellular context, the MAPK/ERK cascade mediates diverse biological functions such as cell growth, adhesion, survival and differentiation through the regulation of transcription, translation, cytoskeletal rearrangements.
Images
|
|
Western blot analysis of p-ERK (GB11004) at dilution of 1: 400 |
Storage
| Storage | Store at -20 ℃ for one year. Avoid repeated freeze/ thaw cycles. |
| Storage Buffer | PBS with 0.02% sodium azide, 100μg/ml BSA and 50% glycerol. |
NOTE:
1.This product is intended for research only.
2.This product is recommended to dilute with the Primary Antibody Dilution Buffer (G2025).
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